The Science Behind Effective Particle Control in Cleanrooms
Why it matters—and how to get it right

Whether you’re manufacturing medical devices, assembling electronics, or working in pharmaceutical production, controlling particles at the microscopic level is essential to protecting product integrity, ensuring regulatory compliance, and keeping people safe.

At MediClean, we help our customers design and maintain cleanrooms that go beyond clean—they perform. Here’s a closer look at the science behind effective particle control, and what it means for your cleanroom strategy.

Airborne particles are constantly in motion. These particles can settle on surfaces, infiltrate packaging, or interfere with production processes. According to ISO cleanroom classifications, maintaining acceptable levels of these particles requires strict control over air cleanliness, filtration, personnel behavior, and equipment layout.

The challenge? Many particles are invisible, unpredictable, and persistent. But with the right systems in place, they are absolutely manageable.

  1. Airflow and Filtration
    Cleanrooms rely on controlled airflow to move and remove contaminants. High-Efficiency Particulate Air (HEPA) and Ultra-Low Penetration Air (ULPA) filters capture 99.97% of particles ≥0.3 microns and smaller. Laminar (unidirectional) airflow helps sweep contaminants away from sensitive areas. The placement of filters and return air vents—and how air flows around people, furniture, and equipment—can make or break your particle control strategy.
  2. Surface Selection and Cleanroom Furniture
    Non-shedding, cleanable, and corrosion-resistant surfaces are essential. That’s why MediClean offers cleanroom furniture built from stainless steel and ESD-safe materials. From gowning benches to workstations, every product is designed to minimize particle generation and support easy sanitization.
  3. Behavior and Protocols
    Humans are the largest source of contamination in any cleanroom. The best way to reduce human-generated particles is with proper gowning, training, and traffic flow design. At MediClean, we help customers think through every step—starting at the gowning room.

In highly regulated industries, particle control is a non-negotiable. The cost of a single contamination event can range from scrapped batches to human risk, and even regulatory shutdowns. But the science of cleanrooms doesn’t need to be overwhelming. With the right partner, you can simplify complexity, improve performance, and grow with confidence.

At MediClean, we bring more than cleanroom products—we bring experience, insight, and a customer-first approach to every project. We design solutions that perform today and scale for tomorrow. And we listen—because no two cleanrooms are the same.

Small business is a big deal to us. That means you’re not just a number in our system. You’re a partner, and we’re committed to supporting your success every step of the way.

Looking to build or upgrade your cleanroom?
We’d love to help you design a space that performs as precisely as the work you do inside it.